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KMID : 1134820110400060781
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Journal of the Korean Society of Food Science and Nutrition
2011 Volume.40 No. 6 p.781 ~ p.789
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The Change in Biological Activities of Brown Rice and Germinated Brown Rice
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Kim Dae-Jung
Oh Sea-Kwan
Yoon Mi-Ra
Chun A-Reum
Choi Im-Soo
Lee Dong-Hyun
Lee Jun-Soo
Yu Kwang-Wan
Kim Yeon-Kyu
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Abstract
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We studied the biological activities, including antioxidant compounds, antioxidant activities, anti-proliferative activities, and immunological activities of brown rice and germinated brown rice. We examined the DPPH, ABTS radical scavenging activity, and reducing power of 70% ethanol extracts from some cultivars of brown rice and germinated brown rice. The total polyphenol, total flavonoid, and γ-oryzanol contents of the extracts were measured with spectrophotometric methods. The Hongjinjubeyo brown rice and germinated brown rice extracts showed markedly higher antioxidative activity than those of 70% ethanol extracts from other cultivars. The 70% ethanol extracts from brown rice and germinated brown rice had the most effective anti-proliferative activity (cytotoxicity) against breast cancer cells (MCF-7) compared to colorectal cancer cells (HCT-116). A 500 ㎍/㎖ concentration of 70% Hongjinjubyeo ethanol extract had higher macrophage and mitogenic activities of immunological activity than other cultivars.
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KEYWORD
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brown rice, germinated brown rice, antioxidant, mitogenic activity, anti-proliferative activity
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